Table 1.
Study characteristics
| Study | Year | Location | Study design | Patients enrolled | Patients analyzed (STA/ELA) | Sex ratio (M/F) | Mean age (year) (STA/ELA) | Follow-up (month) | Missing data (%) |
|---|---|---|---|---|---|---|---|---|---|
| Basile et al. [21] | 2016 | Italy | RCT | 45 | 38(18/20) | 28/10 | 41.9/39.6 | 24/24 | 7(15.6%) |
| Xia et al. [22] | 2014 | China | RCT | 127 | 108(59/49) | 104/4 | 38/37 | 19/29 | 19(15.0%) |
| Wu et al. [23] | 2012 | China | CS | 739 | 329(181/148) | 307/22 | 39.4/41.5 | 12/12 | 410(55.5%) |
| Takasaka et al. [24] | 2016 | Brazil | CS | 47 | 47(27/20) | NR | NR | NR | 0(0%) |
| Kline et al. [25] | 2013 | USA | CS | 112 | 112(33/79) | 93/19 | 46.4/42.2 | 28/31 | 0(0%) |
| Weber et al. [26] | 2008 | Switzerland | CS | 50 | 50(24/26) | NR | 42.7/40 | 31/25 | 0(0%) |
| Yeo et al. [27] | 2015 | ROK | CS | 100 | 100(40/60) | 63/37 | 46/42 | 46/57 | 0(0%) |
M/F male/female, NR not reported