Table 2.

Serum levels of total IGF-1, serum free IGF-1, IGFBP3, adiponectin, leptin, and resistin at baseline, and change (∆) at posttest after resistance exercise

	All patients		Lean		Overweight		Obese		Intergroup differences in change
	Baseline	∆Posttest	Baseline	∆Posttest	Baseline	∆Posttest	Baseline	∆Posttest	Lean vs overweight	Lean vs obese	Overweight vs obese
	Median (IQR)	Median (IQR)	Median (IQR)	Median (IQR)	Median (IQR)	Median (IQR)	Median (IQR)	Median (IQR)
		Cohen’s d		Cohen’s d		Cohen’s d		Cohen’s d
		P-valuea		P-valuea		P-valuea		P-valuea	P-valueb	P-valueb	P-valueb
Total IGF-1	137 (54)	−3 (−21.2 to 5)	135 (54)	−11 (−18,8 to 5)	151 (61)	−3 (−47,5 to 7)	137 (61)	−1.5 (−18 to 8,8)
(ng/ml)	n = 42	n = 42	n = 18	n = 18	n = 16	n = 16	n = 8	n = 8
		−0.23		−0.2		−0.36		−0.09
		0.018		p = 0.076		p = 0.147		p = 0.528	p = 0.986	p = 0.531	p = 0.528
Free IGF-1	2.6 (3.2)	0 (−1.4 to 1.0)	3.3 (2.3)	−0.7 (−1,9 to 0,1)	2.6 (3.3)	0.4 (−1,1 to 1,5)	0.8 (2.3)	0.4 (−0,6 to 2,8)
(ng/ml)	n = 43	n = 43	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		−0.05		−0.32		0.1		0.6
		0.752		p  = 0.047		p = 0.485		p = 0.237	p = 0.053	p  = 0.035	p = 0.511
IGFBP3	823 (159)	−46.4 (−84.4 to 33.2)	828 (86)	−56 (−97 to 5)	790 (161)	−47 (−86 to 119)	858 (238)	−41 (−73 to 23)
(ng/ml)	n = 43	n = 43	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		−0.29		−0.57		0.02		−0.36
		p  = 0.045		p  = 0.025		p = 0.943		p = 0.161	p = 0.335	p = 0.567	p = 0.887
Adiponectin	10288 (6280)	192 (−1880 to 2064)	12036 (7396)	224 (−1638 to 2406)	11624 (5668)	−832 (−1948 to 1752)	6600 (4020)	−204 (−2648 to 2398)
(ng/ml)	n = 43	n = 43	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		0.02		0.09		−0.03		−0.04
		0.819		p = 0.586		p = 0.813		p = 0.889	p = 0.59	p = 0.765	p = 0.887
Leptin	27.7 (71.6)	−4.9 (−18.5 to 1.0)	21 (86)	−15.9 (−23,6 to −0,1)	39 (60)	0 (−3 to 19,6)	23 (106)	−12 (−23,1 to −2,3)
(ng/ml)	n = 43	n = 43	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		−0.13		−0.22		−0.02		−0.51
		0.040		p  = 0.008		p = 0.463		p = 0.093	p  = 0.005	p = 0.849	p  = 0.019
Resistin	13.1 (5.1)	−0.7 (−2.0 to 0.9)	13 (5)	−0.7 (−1.5 to 1)	11 (7)	0.2 (−2,5 to 1,6)	15 (5)	−1.6 (−1,9 to 0,1)
(ng/ml)	n = 43	n = 43	n = 18	n = 18	n = 17	n = 17	n = 8	n = 8
		−0.11		0.04		−0.19		−0.42
		0.227		p = 0.446		p = 0.723		p = 0.161	p = 0.987	p = 0.285	p = 0.588

Serum levels of the whole group and subdivided in lean, overweight and obese patients. Median values, upper and lower boundaries of the interquartile (IQR) range are indicated. Effect size of change is shown as Cohen’s d. Within group comparisons (p-value^a: Wilcoxon signed rank test) and group comparisons (p-value^b: Mann–Whitney U-test) are shown. P-values in bold type are significant