Fig. 4.

Overexpression of GPR87 contributes to pancreatic cancer progression in vivo. a. Representative images of tumor-bearing mice (left) and tumors from mice in each group (right). b. Tumor volumes were measured on the indicated days. c. Mean tumor weights. d. IHC staining demonstrating that overexpression of GPR87 induces while suppression of GPR87 inhibits the aggressive phenotype of pancreatic cancer cells in vivo, as indicated by the expression of Ki67 and CD31 as well as TUNEL-positive cells. * p < 0.05