Table 1.
Resection of abdominal neuroblastoma performed between August 2003 and 2016
| Laparotomy (n = 34) | Laparoscopy (n = 9) | p | |||
|---|---|---|---|---|---|
| Total laparoscopic resection 8 (89%) | Conversion 1 (11%) | ||||
| Removal | Total 18 (53%) | Partial 16 (47%) | Total 8 (100%) | Partial 1 (100%) | |
| Age (months) a | 45 [12–60] | 28 [21.5–51] | 0.300 | ||
| Sex | males 12 (35%) | females 22 (65%) | males 5 (56%) | females 4 (44%) | 0.440 |
| IDRF (%) | IDRF+ 25 (74%) | IDRF− 9 (26%) | IDRF+ 2 (22%) | IDRF− 7 (78%) | 0.008 b |
| MYCN amplified | amplified 9 (26%), single 14 (41%), unknown 11 (32%) | amplified 2 (22%), single 3 (33%), unknown 4 (44%) | 0.790 | ||
| HVA (mg/gCr) a | 16.1 [13.1–23.8] | 18.2 [11.2–43.3] | 0.702 | ||
| VMA (mg/gCr) a | 9.70 [8.9–17.8] | 9.1 [4.0–24.7] | 0.702 | ||
| NSE (ng/mL) a | 11.4 [9.0–15.7] | 19.1 [11.0–21.0] | 0.051 | ||
| Largest tumor dimension (cm) a | 4.0 [3.0–6.0] | 4.3 [2.6–4.8] | 0.704 | ||
IDRF image-defined risk factor, MYCN N-myc proto-oncogene protein, VMA vanillylmandelic acid, HVA homovanillic acid, NSE neuron-specific enolase
aMedian [Interquartile range]
bThis p value shows that the proportion of IDRF-negative patients in the laparoscopy group was significantly greater than that in the laparotomy group