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. 2010 Jul-Aug;18(4):335–342. doi: 10.1590/S1678-77572010000400003

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of 8.5% DOX gel on myeloperoxidase (MPO) activity in the maxillary gingival tissue of rats submitted to experimental periodontal disease (EPD). Vehicle (V) gel and Doxycycline (DOX) gel were administered topically in animals subjected to EPD induction. EPD was induced also in Non-Treated (NT) animals and Naïve group received no treatment and was not submitted to EPD induction. Bars represent mean ± Standard Error of Mean (SEM) of the activity of MPO/mg of tissue. *P<0.05 was considered significantly different compared to NT group (ANOVA; Bonferroni’s test)