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. 2014 Jun 22;1(7):225–240. doi: 10.15698/mic2014.07.155

Table 1.

Global gene regulation in the P. anserina wild type stressed by PQ and during aging.

The table shows the number of differentially regulated genes (factor < 3; pV < 0.01) of all analyzed transcriptome data. In the individual columns two data sets are compared (i.e. aging and PQ stress in juvenile cultures), respectively. The lines show the number of differentially expressed genes at the specified treatment. The amount of differentially regulated transcripts in the specific direction in both treatments is depicted in the line ‘conjoint regulated’. The statistical expectation (‘stat. expectation’) provides the number of genes which is expected to be regulated if the two treatments initiate random gene regulation. The p-value was calculated by Fisher’s exact test. Since the calculation of p-values lower than 2.2e-16 are identical, we included the odds ratio to clarify the level of similarity in transcript generation. The odds ratio is a measure for statistical dependence. A high odds ratio indicates a high probability for a regulation of a gene in the same direction during both compared condition.

Aging / PQ juv PQ juv / PQ ma PQ juv / PQ sen PQ ma / PQ sen PQ juv / Grisea
up down up down up down up down up down
Aging 509 774
PQ juv 683 1172 683 1172 683 1172 683 1172
PQ ma 933 1460 933 1460
PQ sen 1270 1854 1270 1854
Grisea 608 556
Conjoint regulated 89 210 305 746 387 746 405 793 167 267
Stat. expectation 35 90 64 172 87 217 119 273 43 67
p-value 2.2e-16 2.2e-16 2.2e-16 2.2e-16 2.2e-16 2.2e-16 2.2e-16 2.2e-16 2.2e-16 2.2e-16
Odds ratio 3.19 3.21 11.06 19.71 12.51 12.23 7.20 8.30 6.29 8.41