Skip to main content
. 2017 Mar 5;23:1146–1155. doi: 10.12659/MSM.899646

Table 3.

Dose-dependent assay for anticancer evaluation.

Compound No. Na LogGI50 Log TGI Log LC50
N1b Range MG_MID N2b Range MG_MID N3b Range MG_MID
BT1 3 3 −4.64 to −6.49 −5.07 56 −4.0 to −4.83 −4.4 19 −4.0 to −4.36 −4.06
BT4 3 3 −4.64 to −6.52 −5.33 37 −4.0 to 5.08 −4.36 09 −4.0 to −4.28 −4.02
BT8 3 3 −4.0 to −4.84 −4.45 08 −4.0 to −4.24 −4.02 00 −4.0 to −4.02 −4.0
BT17 3 3 −4.42 to −5.02 −4.71 25 −4.0 to −4.32 −4.07 03 −4.0 to −4.08 −4.0
BT18 3 3 −3.92 to −6.93 −4.90 49 −3.92 to −6.01 −4.07 49 −3.92 to −4.75 −4.29
a

N – no. of human cancer cell lines tested at the IInd stage assay;

b

N1, N2, N3 – no. of sensitive cell lines, against which the compound possessed considerable growth inhibition as per the standard parameter (logGI50, logTGI, and log LC50 ≥4.00) (GI50 (50% of net cell growth inhibition at molar concentration of the compound.) TGI (Total inhibition at molar concentration of the compound) and LC50 (50% of net cell death at molar concentration of the compound).