Table 5. Spatial and temporal indices of MRI data quality selected from the Preprocessed Connectome Project.
Spatial Metrics | Description |
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They have been computed for all structural MRI (sMRI), Diffusion Tensor Imaging (DTI), and Resting State functional MRI (R-fMRI) datasets unless indicated otherwise. All are released for each dataset in ABIDE II (file and link of release pending). See Figs 3 and 4 and Supplementary Fig. 1 for illustrations of the distribution of a selection of spatial and temporal metrics within and across collection. |
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Contrast-to-noise ratio (CNR) 50 (sMRI only) | MGM intensity—MWM intensity/SDair intensity. Larger values reflect a better WM GM distinction. |
Signal-to-noise ratio (SNR) 50 | MGM intensity/SDair intensity. Larger values reflect less noise |
Artifactual voxel detection (Qi1) 51 (sMRI only) | * voxels with intensity corrupted by artifacts/ *voxels in the background. Larger values reflect more artifacts which likley due to motion or image instability. |
Entropy Focus Criteria (EFC) 65, † | Shannon’s entropy of each voxel's intensity used to measure ghosting and blurring due to head motion. Larger values reflect more blurring likley to motion or techincal differences. |
Smoothness of Voxels 62 (FWHM) † | Full-width half maximum of the spatial distribution of the image intensity values. Larger values reflect more spatial smoothing maybe due to motion or technical differences. |
Foreground to Background Energy Ratio (FBER) † | M energy of image intensity (i.e., mean of squares) within the head relative to that of outside the head. Larger values reflect higher signal in relation to noise. |
Ghost to Signal Ratio (GSR) 66, † | M signal in the ‘ghost’ image divided by the M signal within the brain. Larger values reflect more ghosting likley due to physiological noise, motion, or technical issues. |
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Temporal Metrics (R-fMRI* and DTI only)
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Mean framewise displacement- Jenkinson (mFD) 52, ‡ | Sum absolute displacement changes in the x, y and z directions and rotational changes around them. Rotational changes are given distance values based on changes across the surface of a 50 mm radius sphere. Larger values reflect more movement. |
% and * volumes with FD>0.2 mm ‡ | % and *volume to volume motion >0.2 mm FD. Larger values reflect more movement. |
Standardized DVARS 63, ‡ | Spatial SD of the data temporal derivative normalized by the temporal SD and autocorrelation. Larger values reflect larger frame-to-frame differences in signal intensity due to head motion or scanner instability. |
Outlier Detection 67, † | M fraction of outliers in each volume per 3dToutcount AFNI command. Higher values reflect more outlying voxels, which may be due to scanner instability or RF artifacts. |
Global Correlation (GCORR) 64, ‡ | M correlation of all combinations of voxels in a time series. Illustrates differences between data due to motion/physiological noise. Larger values reflect a greater degree of spatial correlation between slices, which may be due to head motion or ‘signal leakage’ in simultaneous multi-slice acquisitions. |
Median Distance Index 67, ‡ | M distance (1—spearman’s rho) between each time-point's volume and the median volume using AFNI’s 3dTqual command. Higher values reflect greater differences between subsequent frames, which may be due to head motion or technical issues. |
*For all R-fMRI data temporal metrics have been computed after discarding the first 5 time points of the time series which were field map corrected if field maps were provided (only in the SDSU_1 data collection). Computation of all spatial metrics excluded absolute zero background values.
† For R-fMRI data these metrics are computed on mean functional data.
‡ For R-fMRI these metrics are computed on time series data. M, Mean; GM, Gray Matter; WM, White Matter; s.d., Standard Deviation.