Table 1.
Sample Characteristics
Total (n=27) | Tried on clozapine (n=13) | Not tried on clozapine (n=14) | Fisher’s exact | ||||
---|---|---|---|---|---|---|---|
| |||||||
Categorical Variable | n | % | n | % | n | % | |
Gender | |||||||
Male | 22 | 81.5 | 12 | 92 | 10 | 71 | 0.33 |
Female | 5 | 18.5 | 1 | 8 | 4 | 29 | |
Race | |||||||
Caucasian | 14 | 52 | 6 | 46 | 8 | 57 | 0.58 |
Afro-carribean | 3 | 11 | 2 | 15 | 1 | 7 | |
Aboriginal | 4 | 15 | 1 | 8 | 3 | 21 | |
Other (eg. Iranian, South East Asian, Mixed race) | 6 | 22 | 4 | 31 | 2 | 14 | |
Diagnosis | |||||||
Schizophrenia/Schizoaffective Disorder | 21 | 12 | 7 | 0.06 | |||
Bipolar Disorder with psychotic symptoms | 3 | 0 | 3 | ||||
Psychosis NOS | 5 | 1 | 4 | ||||
Level of Psychosis at First Data Entry | |||||||
0 = residual symptoms | 5 | 2 | 3 | 1.00 | |||
1= partial symptoms | 5 | 2 | 3 | ||||
2 = florid symptoms | 17 | 9 | 8 | ||||
Placement Status at First Data Entry | |||||||
Inpatient | 17 | 8 | 9 | 1.00 | |||
Outpatient | 10 | 5 | 5 | ||||
| |||||||
Continuous/ Ordinal Variable | Wilcoxon Rank-Sum test | ||||||
| |||||||
Age at First Data Entry | |||||||
15 | 2 | 7.4 | 2 | 15 | 0 | 0 | 0.03* |
16 | 11 | 40.7 | 7 | 54 | 4 | 29 | |
17 | 14 | 51.9 | 4 | 31 | 10 | 71 | |
Motivation to reduce use at last observation prior “time zero”. | |||||||
Low | 19 | 73.1 | 10 | 83 | 9 | 64 | 0.24 |
Medium | 2 | 7.7 | 1 | 8 | 1 | 7 | |
High | 5 | 19.2 | 1 | 8 | 4 | 26 | |
Severity of THC use at baseline | |||||||
0 = hardly ever | 1 | 0 | 1a | 0.60 | |||
1 = less than once a month | 1 | 1a | 0 | ||||
2 = once a month | 3 | 2 | 1 | ||||
3 = 2–3 times per month | 4 | 2 | 2 | ||||
6 = > 5 times a week | 18 | 8 | 10 | ||||
| |||||||
Median | IQR | Med | IQR | Med | IQR | ||
| |||||||
Duration of Treatment (months) | 14 | 9–23 | 21 | 14–23 | 11.5 | 9–16 | 0.02* |
These patients had met criteria for cannabis use disorder prior to first data entry and so were still included in our sample as there was high potential for relapse.
indicates p<0.05