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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Ann Rheum Dis. 2015 Oct 9;75(9):1706–1713. doi: 10.1136/annrheumdis-2015-207593

Figure 1. Netrin-1 is highly expressed in inflammatory infiltrates in wear particle-induced osteolysis.

Figure 1

A) The figures show representative images for H&E, Netrin-1 immunostaining and TRAP staining in human tissue biopsies from implant revision and primary implants (n=5 each). B) The figures show representative images for Netrin-1, Unc5b and DCC immunostaining in a murine UHMWPE particle-induced osteolysis model (n=5 mice per group). Images were taken at 100X and 400X magnification. Scale bar indicates 50 and 100 μm. ***p<0.001, compared to untreated (Sham) (ANOVA).