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. 2017 Feb 16;31(3):338–345. doi: 10.1177/0269881117691467

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — (a) Significant GO terms activated in response to nortriptyline dose. (b) The top GO term identified from our data, ‘intracellular organelle’, visualised as a gene co-expression network. Genes in grey represent hypothetical transcripts connecting other genes within the network, whereas genes in blue represent those transcripts identified from our dataset. (c) Eight compounds with the strongest positive connectivity scores (similar effects on mRNA) and two compounds with the strongest negative connectivity scores (opposite effects on mRNA; only two compounds identified) in neural progenitor cells.