Figure 4.
Rosiglitazone decreased the radiation-induced gene expression of fibrosis, inflammatory and apoptosis markers in bowel tissues.
mRNA expression of Bax, Col1, Mmp13 and Tnfα, p53 in jejunum tissues of mice treated with saline (control), irradiation (IR, 12 Gy) or IR + RGZ (5 mg/kg) after 24 and 72 hours. Data, measured as fold increase in expression compared with control (taken as 1), are shown as mean ± SEM. *p < 0.05 vs. control, #p < 0.05 vs. IR.