Table 3.
Diagnostic performance of contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS), elastography strain ratio, and strain histogram
| Benign versus malignant |
Pancreatic cancer versus chronic
pancreatitis |
|||||
|---|---|---|---|---|---|---|
| Elastographya | CEH-EUS | Combinationb | Elastographya | CEH-EUS | Combinationb | |
| Sensitivity (95% CI) | 100 (92.7–100) | 89.8 (78.2–95.6) | 89.8 (78.2–95.6) | 100 (92.3–100) | 91.3 (79.7–96.6) | 91.3 (79.7–96.6) |
| Specificity (95% CI) | 92.3 (66.7–98.6) | 69.2 (42.4–87.3) | 100 (77.2–100) | 90.9 (62.3–98.4) | 81.8 (52.3–94.9) | 100 (74.1–100) |
| Positive predictive value (95% CI) | 98.0 (89.5–99.7) | 91.7 (80.5–96.7) | 100 (92.0–100) | 97.9 (88.9–99.6) | 95.5 (84.9–98.7) | 100 (91.6–100) |
| Negative predictive value (95% CI) | 100 (75.8–100) | 64.3 (38.8–83.7) | 72.2 (49.1–87.5) | 100 (72.3–100) | 69.2 (42.4–87.3) | 73.3 (48.1–89.1) |
| Accuracy (95% CI) | 98.4 (91.4–99.7) | 85.5 (74.7–92.2) | 91.9 (82.5–96.5) | 98.3 (90.7–99.7) | 89.5 (78.9–95.1) | 93.0 (83.3–97.2) |
CI: confidence interval.
a
Diagnostic performance of strain ratio and mean strain histogram was identical and these modalities are therefore presented together.
b
Cases were classified as positive if both CEH-EUS and elastography were positive.