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. 2017 Mar 14;7:44385. doi: 10.1038/srep44385

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Rarefaction curves based on observed species index (97% sequence similarity threshold), Chao1 and Shannons diversity index. Alpha diversity measure expressed with observed species and chao1 indexes revealed significantly reduced (p < 0.01) diversity in ex-germ-free mice inoculated with the gut microbiota from the lowest responding CONV mouse (LOW) compared to ex-germ-free mice inoculated with the gut microbiota from the highest responding CONV mouse (HIGH) as well as to barrier protected mice (CONV). Shannon diversity index only revealed a reduced (p < 0.01) diversity in LOW mice compared to CONV mice. **p < 0.01.