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. Author manuscript; available in PMC: 2017 Mar 14.
Published in final edited form as: Curr Pharm Biotechnol. 2012 Jun;13(7):1346–1359. doi: 10.2174/138920112800624409

Figure 7.

Figure 7

Model predictions for hydraulic conductivity Lp (a) as a function of Bs, the half width of the small slit in the junction strand under two cases: when considering transport across the endothelium only (Endothelium only, green line), and when considering transport across the entire BBB (BBB). In the BBB case, three different fiber densities were considered for the basement membrane: the same as the fiber density in the surface glycocalyx layer (Kb=3.16cm2, the dash-dot-dash line), ten times lower (Kb=31.6cm2, the dashed line) and higher (Kb=0.316cm2, the solid line); (b) as a function of the surface glycocalyx layer thickness Lf. Redrawn from [40].