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. Author manuscript; available in PMC: 2017 Mar 14.
Published in final edited form as: ACS Chem Neurosci. 2015 Mar 3;6(5):771–777. doi: 10.1021/acschemneuro.5b00006

Table 1.

Inhibition of [3H]Neurotransmitter Reuptake at DAT and NET for MDPV (3), Its Optical Isomers, and Cocainea

IC50, nM
DAT NET
(±)MDPV (3) 4.85 ± 0.49 16.84 ± 1.10
S(+)MDPV (3S) 2.13 ± 0.17 9.86 ± 1.03
R(−)MDPV (3R) 382.80 ± 53.26 726.10 ± 150.10
(−)cocaine 198.80 ± 14.86 395.90 ± 47.80
a

Data are expressed as the mean ± SEM for n = 3 experiments performed in triplicate.