TABLE 1.
Percentages of IL-10eGFP+ cell in VERT-X mice in response to PGRN
| Cell type | Physiological conditions |
Inflammatory conditions |
||
|---|---|---|---|---|
| PBS | PGRN | PBS | PGRN | |
| CD4+IL-10eGFP+ | 1.47 ± 0.35 | 2.68 ± 0.42* | 2.66 ± 0.81 | 5.64 ± 1.15* |
| CD8+IL-10eGFP+ | 1.34 ± 0.24 | 1.21 ± 0.20 | 1.08 ± 0.13 | 0.93 ± 0.26 |
| CD19+IL-10eGFP+ | 3.42 ± 0.81 | 3.31 ± 0.74 | 1.34 ± 0.83 | 1.08 ± 0.46 |
| CD11c+IL-10eGFP+ | 7.68 ± 2.27 | 8.87 ± 1.98 | 9.44 ± 1.11 | 10.62 ± 2.24 |
| F4/80+IL-10eGFP+ | 8.12 ± 2.44 | 9.02 ± 1.91 | 10.87 ± 1.55 | 11.14 ± 2.27 |
| CD4+CD25−IL-10eGFP+ | 0.51 ± 0.18 | 0.58 ± 0.19 | 1.46 ± 0.36 | 1.79 ± 0.42 |
| CD4+CD25+IL-10eGFP+ | 1.81 ± 0.25 | 3.67 ± 0.85* | 3.12 ± 0.87 | 7.34 ± 1.03* |
Data are presented as percentage ± sd for VERT-X mice (n = 12 per each group) in the presence or absence of PGRN under physiological or inflammatory conditions. *P < 0.01 vs. control group.