TABLE 2.
Percentages of IL-10eGFP+ cell in VERT-X, PGRN+/+ or VERT-X, and PGRN−/− mice
| Cell type | Physiological conditions |
Inflammatory conditions |
||
|---|---|---|---|---|
| WT | KO | WT | KO | |
| CD4+IL-10eGFP+ | 1.24 ± 0.33 | 0.93 ± 0.17 | 2.22 ± 0.71 | 1.21 ± 0.42** |
| CD8+IL-10eGFP+ | 1.17 ± 0.23 | 1.02 ± 0.31 | 0.95 ± 0.25 | 1.07 ± 0.41 |
| CD19+IL-10eGFP+ | 2.86 ± 0.67 | 2.73 ± 0.49 | 1.06 ± 0.32 | 0.96 ± 0.26 |
| CD11c+ IL-10eGFP+ | 6.45 ± 1.67 | 5.40 ± 1.38 | 9.45 ± 2.42 | 8.37 ± 2.79 |
| F4/80+IL-10eGFP+ | 7.47 ± 1.56 | 7.18 ± 1.12 | 11.27 ± 1.77 | 8.69 ± 1.32** |
| CD4+CD25−IL-10eGFP+ | 0.64 ± 0.17 | 0.53 ± 0.12 | 1.73 ± 0.42 | 1.51 ± 0.39 |
| CD4+CD25+IL-10eGFP+ | 1.79 ± 0.38 | 1.87 ± 0.43 | 3.47 ± 0.56 | 1.42 ± 0.28* |
Data are presented as percentage ± sd for VERT-X, PGRN+/+ or VERT-X, or PGRN−/− mice (n = 12 per each group under physiological or inflammatory conditions. KO, knockout. *P < 0.01; **P < 0.05 vs. control group.