Skip to main content
. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Orthop Res. 2016 Mar 21;34(11):1941–1949. doi: 10.1002/jor.23204

Figure 3.

Figure 3

In the epiphysis loading decreased epiphyseal cancellous mass (BV/TV) in adult mice at 1 week. This change was due to decreased trabecular thickness (Tb.Th) at 1 week, but not to increased trabecular separation (Tb.Sp) (A). Osteoclast number (OC.N/BS), which was identified by immunohistochemical staining for Cathepsin K positive osteoclasts, increased in the epiphysis with loading (B, E). Metaphyseal bone mass (BV/TV) did not change with loading (C). Medial posterior subchondral cortical bone thickness (Sub.Pl) decreased with loading (D). Scale bar = 200 μm. Data presented as mean ± SD of 7/group.

^loading, †time, §loading*time, p<0.05 by repeated measures two-way ANOVA. Groups with different letters are significantly different by post-hoc comparisons of means with Bonferroni correction.