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. 2016 Dec 9;7(52):85728–85740. doi: 10.18632/oncotarget.13828

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Copyright: © 2016 Yang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A. semi-NMF clustering identifies two subtypes of ESCC based on expression levels of lncRNAs and mRNAs. B. Overall survival of different subtypes of ESCC by Kaplan-Meier plot. ESCC subtypes are highly correlated with overall survival outcomes. C.-D. Differential expressed genes (DEGs) in two subtypes were divided into three groups, including the DEGs only in the subtype 1, the DEGs only in the subtype 2 and the DEGs in both subtypes. Significantly enriched GO terms and KEGG pathways of each group are shown.