Table 4. Univariate and multi-variate analysis of the clinicopathological and molecular features for OS in LUSC.
| Clinicopathological parameters | Comparison reference | Univariate analysis | Multi-variate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95%CI) | P value | Hazard ratio (95%CI) | P value | ||
| Age | < 65 | Ref | |||
| ≥ 65 | 0.649 (0.280–1.503) | 0.307 | |||
| Gender | Male | Ref | |||
| Female | 0.913 (0.375–2.224) | 0.842 | |||
| Smoke | No | Ref | |||
| Yes | 0.909 (0.384–2.153) | 0.828 | |||
| Clinical Stage | IA | Ref | 0.039 | Ref | 0.221 |
| IB | 2.830 (0.255–31.346) | 0.397 | 3.088 (0.275–34.686) | 0.361 | |
| IIA | 5.361 (0.626–45.921) | 0.125 | 4.805 (0.550–41.949) | 0.156 | |
| IIB | 9.739 (1.186–79.956) | 0.034 | 8.430 (0.995–71.386) | 0.050 | |
| IIIA | 17.498 (2.100–145.829) | 0.008 | 13.287 (1.442–122.460) | 0.022 | |
| IIIB | 19.248 (1.157–320.344) | 0.039 | 14.606 (0.812–262.349) | 0.069 | |
| IL-1β level | Low | Ref | Ref | ||
| High | 3.106 (1.218–7.917) | 0.018 | 1.531 (0.503–4.657) | 0.453 | |
| TNF-α level | Low | Ref | |||
| High | 0.810 (0.357–1.839) | 0.615 | |||
| miR-144-3p level | Low | Ref | |||
| High | 1.216 (0.533–2.777) | 0.642 | |||