Table 1. Inhibitors and effect on cell.
| Inhibitor | Working concentration | Effect on cell |
|---|---|---|
| Chlorpromazine (CPZ) | 5 μM or 10 μM | Inhibitor of clathrin-mediated endocytosis |
| Methyl-β-cyclodextrin (MβCD) | 2.5 mM or 5 mM | Disrupt lipid rafts in cells by depleting the cholesterol component |
| Dynasore | 50 μM or 100 μM | Inhibitor of dynamin |
| 5-(N-methyl-N-isobutyl) amiloride (EIPA) | 20 μM or 40 μM | Inhibitor of the NHEs |
| Jasplakinolide | 100 nM or 200 nM | Induce actin polymerization and prevent the actin rearrangement |
| Rottlerin | 5 μM or 10 μM | PKC inhibitor |
| Phorbol-12-myristate-13-acetate (PMA) | 5 μM or 10 μM | PKC activator |
| wortmannin | 20 μM or 40 μM | Inhibitor of the PI(3)K |
| Rac1 inhibitor | 50 μM or 100 μM | Inhibitor of the Rac1 kinase |
| Ammonium chloride (NH4CL) | 50 μM or 75 μM | Neutralizes intravesicular pH |
| Bafilomycin A1 (Baf A1) | 50 nM or 100 nM | Inhibitor of endosomal acidification |