Figure 6.

Gli1-Foxm1 axis promotes EMT change in colorectal cancer cells (A) Percentage of specimens exhibiting low or high Gli1 expression and association of Gli1 expression with expression levels of E-cadherin and vimentin (B) in CRC tumor specimens. **p < 0.01, ***p < 0.001. (C) E-cadherin and vimentin (D) expression levels were measured in different colorectal cancer cell lines by real-time PCR and western blot (E) together with Foxm1 protein expression levels in different type LOVO cells. The intensity of the bands was determined using densitometric analysis.**p < 0.01, *p < 0.05. (F) Morphology changes in in different type LOVO cells.