Table 2. Multivariate analysis (Cox regression) including clinical and pathological parameters in addition to 18q deletion in all cancers, ERG negative cancers and ERG positive cancers.
Tumor subset | Scenario | n analyzable | P value | |||||||
---|---|---|---|---|---|---|---|---|---|---|
preop. PSA-Level | pT Stage | cT Stage | Gleason grade prostatectomy | Gleason grade biopsy | pN Stage | R-Status | 18q Deletion | |||
all cancers | 1 | 3819 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0097 | 0.0004 | ||
2 | 6126 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0004 | ||||
3 | 6008 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0001 | |||||
4 | 5925 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | |||||
ERG-negative cancers | 1 | 1916 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0001 | 0.0749 | 0.0148 | ||
2 | 3030 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0024 | 0.0157 | ||||
3 | 2988 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0067 | |||||
4 | 2949 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0024 | |||||
ERG-positive cancers | 1 | 1674 | 0.0282 | < 0.0001 | < 0.0001 | 0.0355 | 0.1069 | 0.0264 | ||
2 | 2666 | 0.0009 | < 0.0001 | < 0.0001 | 0.0015 | 0.0634 | ||||
3 | 2598 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0335 | |||||
4 | 2560 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0593 |