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. 2016 Nov 16;7(52):86374–86387. doi: 10.18632/oncotarget.13413

Figure 6. The inhibitory effect of curcumin on aggressive capacity of SKOV3 spheroid.

Figure 6

(A) Comparison of adhesion and invasion of SKOV3 between monolayer and spheroid. Cells grown as spheroid for 2 days were trypsinized to a single cell suspension and allowed to adhere or invade to the matrigel. *P < 0.05, compared with monolayer. (B) Adhesion and invasion assays were performed in SKOV3 spheroid after curcumin treatment. Scale bar =125 μm. All the data were presented as the mean ± SEM of at least three experiments.*P < 0.05, compared with negative control.