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. 2016 Nov 8;7(52):86388–86405. doi: 10.18632/oncotarget.13199

Figure 2. Effects of radio-induced IFITM3 expression on BTPCs.

Figure 2

A, B. and C. Fractionized IR of 1080 cells led to an increased expression of IFITM3 (A) mRNA and protein as detected by (B) Western blot or (C) immunocytochemistry. TCL - total cell lysate. Scale bar represents 20 μm. D. rs1080 cells displayed enhanced sphere-forming capacity as compared to the parental cell line 1080. E. Survival potential of rs1080 and the parental control 1080 48 h after increasing doses of γ-radiation. F. Immunostainings showing stabile upregulation of IFITM3 in rs1080 tumors. Scale bar represents 50 μm. G. Kaplan-Meier survival curves of mice with rs1080 and control tumors.