Table 1. Characteristics of RM studies participants ≥ 35 y.o.
| Gail Characteristics | Discovery study subjects(n = 90) [32] | Replication study subjects(n = 71) [34] | ||
|---|---|---|---|---|
| No. | % | No. | % | |
| Race | ||||
| White | 64 | 71.1 | 56 | 78.9 |
| Black | 25 | 27.8 | 5 | 7.0 |
| Hispanic | 1 | 1.1 | 8 | 11.3 |
| Other | 0 | 1.1 | 2 | 2.8 |
| Age, years | ||||
| < 50 | 62 | 68.9 | 44 | 62.0 |
| ≥ 50 | 28 | 31.1 | 27 | 38.0 |
| Median | 45 | 46 | ||
| Range | 35-76 | 35-66 | ||
| Age at menarche, years | ||||
| < 12 | 15 | 16.7 | 17 | 24.0 |
| 12-13 | 43 | 47.7 | 32 | 45.0 |
| ≥ 14 | 16 | 17.8 | 20 | 28.2 |
| Unknown | 16 | 17.8 | 2 | 2.8 |
| Age at first live birth, years | ||||
| Nulliparous | 22 | 24.4 | 13 | 18.3 |
| < 20 | 9 | 10.0 | 16 | 22.6 |
| 20-24 | 12 | 13.3 | 17 | 23.9 |
| 25-29 | 16 | 17.8 | 10 | 14.1 |
| ≥ 30 | 11 | 12.2 | 13 | 18.3 |
| Unknown | 20 | 22.2 | 2 | 2.8 |
| No. of 1st degree relatives with breast cancer | ||||
| 0 | 57 | 63.3 | 60 | 84.5 |
| 1 | 8 | 8.9 | 9 | 12.7 |
| Unknown | 25 | 27.8 | 2 | 2.8 |
| No. of biopsies | ||||
| 0 | 40 | 44.4 | 65 | 91.6 |
| 1 | 6 | 6.7 | 4 | 5.6 |
| ≥ 2 | 2 | 2.2 | 2 | 2.8 |
| Unknown | 42 | 46.7 | 0 | 0 |
| Breast Cancer riskǂ | ||||
| Low | 75 | 83.3 | 48 | 67.6 |
| High | 15 | 16.7 | 23 | 32.4 |
ǂ High breast cancer risk was defined as woman who has at least 10% increased risk of breast cancer relative to women at average risk of the same ethnicity and similar age, estimated by the Gail model.