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. 2016 Nov 19;7(52):86547–86560. doi: 10.18632/oncotarget.13470

Figure 4. DACH1 expression in immunoglobulin A nephropathy (IgAN) and idiopathic membranous nephropathy (IMN) and its correlation with clinical parameters.

Figure 4

(A and C) positive and negative control (NC) stained for DACH1 in a focal proliferative IgAN. (B) A modicum glomerular staining for DACH1 in scarred glomerulus in sclerotic class IgAN. (D) Glomerular DACH1 expression correlates strongly with eGFR in IgAN. (E) Glomerular DACH1 expression correlates negatively with serum creatinine in IgAN. (F) DACH1 detection is higher in patients with disease duration of less than 6 months. (G) section with positive staining for DACH1 in a phase II IMN. (H) Glomerular DACH1 expression correlates strongly with eGFR in IMN. (I) Glomerular DACH1 expression correlates negatively with 24 h urinary protein in IMN. All photos shown contain immunoperoxidase stains with hematoxylin counterstain, 400 magnification. GCS, glomerular cross section, Bar, 50 μm.