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. 2016 Nov 17;7(52):86695–86703. doi: 10.18632/oncotarget.13435

Figure 5. miR-196a promotes cell growth and stemness of CRC cells.

Figure 5

A. The expression of miR-196a was much more increased in LGR5+ than LGR5- CRC cells by qRT-PCR analysis. B. The overexpression effect of p-miR-196a transfection was examined by real time qRT-PCR. C. Overexpression of miR-196a significantly promotes cell growth of LGR5- CRC cells by MS analysis. D. The representative images of tumor spheres showed that overexpression of miR-196a promotes the sphere forming ability of LGR5- CRC cells. E. The representative flow cytometry analysis images showed that overexpression of miR-196a increased the LGR+ CRC cell population.