Table 2. Allele frequencies in cases and controls, and odds ratio estimates for breast cancer risk.
SNP ID | Gene | Chromosome position | Base change | MAF-cases | MAF-controls | HWE test p-value | OR | 95% | CI | p |
---|---|---|---|---|---|---|---|---|---|---|
rs6713088 | ACYP2 | 2p16.2 | G/C | 0.410 | 0.428 | 0.884 | 0.929 | 0.695 | 1.241 | 0.617 |
rs12621038 | ACYP2 | 2p16.2 | T/C | 0.383 | 0.469 | 0.666 | 0.701 | 0.524 | 0.936 | 0.016* |
rs1682111 | ACYP2 | 2p16.2 | A/T | 0.322 | 0.256 | 1.000 | 1.380 | 1.006 | 1.892 | 0.045* |
rs843752 | ACYP2 | 2p16.2 | G/T | 0.303 | 0.300 | 0.305 | 1.016 | 0.744 | 1.386 | 0.922 |
rs10439478 | ACYP2 | 2p16.2 | C/A | 0.385 | 0.441 | 0.193 | 0.795 | 0.595 | 1.063 | 0.122 |
rs17045754 | ACYP2 | 2p16.2 | C/G | 0.145 | 0.205 | 0.508 | 0.656 | 0.448 | 0.960 | 0.029* |
rs843720 | ACYP2 | 2p16.2 | G/T | 0.295 | 0.305 | 0.866 | 0.953 | 0.698 | 1.301 | 0.763 |
MAF = minor allele frequency; HWE = Hardy-Weinberg Equilibrium.
OR= odds ratio; 95% CI = 95 % confidence interval.
p ≤ 0.05 indicates statistical significance.