Table 5. Association between SNPs in ACYP2 and breast cancer risk in dominant, recessive, and additive models after adjusting for age group, body mass index, and menopause status.
SNP | Minor allele | Dominant model | Recessive model | Additive model | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | |||||
rs6713088 | G | 0.96 | 0.63 | 1.49 | 0.870 | 0.88 | 0.51 | 1.50 | 0.633 | 0.95 | 0.70 | 1.27 | 0.710 |
rs12621038 | T | 0.62 | 0.40 | 0.96 | 0.032* | 0.58 | 0.33 | 1.01 | 0.054 | 0.68 | 0.50 | 0.92 | 0.012* |
rs1682111 | A | 1.57 | 1.04 | 2.37 | 0.031* | 1.36 | 0.63 | 2.94 | 0.436 | 1.41 | 1.01 | 1.95 | 0.042* |
rs843752 | G | 0.90 | 0.60 | 1.36 | 0.632 | 1.44 | 0.69 | 3.00 | 0.327 | 1.01 | 0.73 | 1.39 | 0.953 |
rs10439478 | C | 0.69 | 0.45 | 1.08 | 0.103 | 0.78 | 0.44 | 1.38 | 0.401 | 0.78 | 0.57 | 1.06 | 0.112 |
rs17045754 | C | 0.60 | 0.38 | 0.93 | 0.022* | 0.92 | 0.27 | 3.13 | 0.895 | 0.67 | 0.45 | 0.98 | 0.041* |
rs843720 | G | 0.92 | 0.61 | 1.38 | 0.671 | 0.89 | 0.43 | 1.87 | 0.763 | 0.93 | 0.67 | 1.28 | 0.643 |
OR = odds ratio; 95% CI = 95 % confidence interval.
p ≤ 0.05 indicates statistical significance.