Table 3. Summary of cohort characteristics in patients with oropharyngeal squamous cell carcinoma.
P16+ OPSCC | P16– OPSCC | P value (Fisher's test) | |
---|---|---|---|
Age Median = 60.7 | 0.16 | ||
< 20 | 0 | 0 | |
20–40 | 1 | 1 | |
40–60 | 7 | 5 | |
> 60 | 6 | 11 | |
Age > 60 | 6 | 12 | |
Age < 60 | 8 | 5 | |
Gender, | 0.44 | ||
Male | 8 | 13 | |
Female | 6 | 4 | |
Smoking, | 0.06 | ||
Yes | 5 | 12 | |
No | 9 | 4 | |
Not available (n =1) | |||
Alcohol | 0.42 | ||
Yes | 3 | 6 | |
No | 11 | 8 | |
Not available (n =3) | |||
Ethnic | 0.41 | ||
Chinese | 12 | 12 | |
Others | 2 | 5 | |
T stage | 1.00 | ||
T1 | 2 | 2 | |
T2 | 8 | 6 | |
T3 | 1 | 0 | |
T4 | 3 | 9 | |
N stage | 0.70 | ||
N0 | 3 | 5 | |
N1 | 4 | 2 | |
N2 | 4 | 8 | |
N3 | 3 | 2 | |
Definitive treatment | 0.48 | ||
Surgery +/– adjuvant therapy | 7 | 11 | |
Radiation/ChemoRT | 7 | 6 | |
Median follow up | 55.8 month | 19.1 month | |
Overall survival (OS) N3-year OS |
93% | 59% | 0.022 (0.21, 0.05–0.84) |