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. 2016 Nov 23;7(52):87100–87113. doi: 10.18632/oncotarget.13527

Figure 6. KIAA0247 suppressed AKT signaling and STAT3 signaling in glioma cells.

Figure 6

(A–D) KIAA0247 overexpression inhibits AKT and STAT3 signaling pathways. (E–H) Knockdown of KIAA0247 enhances AKT and STAT3 signaling pathways. (I–L) U87 and SHG44 cells with overexpression or knockdown of KIAA0247 were used to analyze the expression of PCNA, CyclinD1, Bcl2, VEGF. Data were based on at least 3 independent experiments, and shown as the mean ± SD. (*P < 0.05, **P < 0.01, ***P < 0.001, compared with NC).