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. 2016 Nov 23;7(52):87100–87113. doi: 10.18632/oncotarget.13527

Figure 7. KIAA0247 overexpression reduces the growth of glioma cell xenografts in nude mice.

Figure 7

(A, B) ELISA assay shows the level of secreted VEGF in U87 and SHG44. (C, D) Representative images of subcutaneous tumor xenografts in nude mice inoculated with U87 and SHG44 cells expressing empty vectors or KIAA0247. (E, F) Time course analysis of tumor growth after injection. (G, H) Representative images of subcutaneous tumor xenografts in nude mice inoculated with U87 and SHG44 cells expressing control shRNA or KIAA0247-specific shRNA. (I, J) Time course analysis of tumor growth after injection. Data were based on at least 3 independent experiments, and shown as the mean ± SD. (*P < 0.05, **P < 0.01, ***P < 0.001 compared with NC).