Table 4. The associations between rs3754093 and clinical characteristics of hepatocellular carcinoma patients.
| Variables | AA | AG/GG | OR(95%CI)a | OR(95%CI)b |
|---|---|---|---|---|
| tumor size | ||||
| ≥5cm | 85(34.56) | 161(63.44) | 1.000 | 1.000 |
| <5cm | 217(29.17) | 527(70.83) | 1.282(0.944∼1.742) | 1.165 (0.876∼1.963) |
| tumor number | ||||
| solitary | 267(30.58) | 606(69.42) | 1.000 | 1.000 |
| multiple | 35(29.91) | 82(70.09) | 1.032(0.677∼1.573) | 0.972 (0.596∼2.248) |
| TNM staging | ||||
| T1+T2 | 262(31.30) | 575(68.70) | 1.000 | 1.000 |
| T3+T4 | 40(26.14) | 113(74.86) | 1.287(0.872∼1.899) | 1.196 (0.756∼1.972) |
| Combined with liver cirrhosis | ||||
| Yes | 100(23.98) | 317(76.02) | 1.000 | 1.000 |
| No | 202(35.25) | 371(64.75) | 0.579(0.437∼0.769) | 0.585 (0.446∼0.756) |
| AFP level (ng/ml) | ||||
| ≥400 | 205 (29.45) | 491(70.55) | 1.000 | 1.000 |
| <400 | 97 (37.16) | 164(62.84) | 0.706 (0.523∼0.952) | 0.681 (0.434∼1.051) |
| tumor metastasis | ||||
| Yes | 53(40.15) | 79(59.85) | 1.000 | 1.000 |
| No | 249(29.02) | 609(70.98) | 1.641(1.124∼2.394) | 1.535 (1.023∼2.538) |
a: OR (95% CI) not adjusted; b: OR (95% CI) adjusted for age, gender, nations, smoking, alcohol consumption, HBV infection, and HCC family history.