Table 6. The associations between rs1776148 and clinical characteristics of hepatocellular carcinoma patients.
| Variables | AA | AG/GG | OR(95%CI)a | OR(95%CI)b |
|---|---|---|---|---|
| tumor size | ||||
| ≥5cm | 6(2.44) | 240(97.56) | 1.000 | 1.000 |
| <5cm | 24(3.23) | 720(96.77) | 1.333(0.539∼3.301) | 1.587(0.317∼7.937) |
| tumor number | ||||
| solitary | 27(3.09) | 846(96.91) | 1.000 | 1.000 |
| multiple | 3(2.56) | 114(97.44) | 1.213(0.362∼4.062) | 1.028(0.121∼8.760) |
| TNM staging | ||||
| T1+T2 | 30(3.58) | 807(96.42) | 1.000 | 1.000 |
| T3+T4 | 6(3.92) | 147(96.08) | 0.911(0.373∼2.227) | 1.128(0.569∼2.233) |
| Combined with liver cirrhosis | ||||
| Yes | 3(0.72) | 414(99.28) | 1.000 | 1.000 |
| No | 27(4.71) | 546(95.29) | 0.147(0.044∼0.486) | 0.154(0.019∼1.260) |
| AFP level (ng/ml) | ||||
| ≥400 | 27(3.88) | 669(96.12) | 1.000 | 1.000 |
| <400 | 3(1.02) | 291(98.98) | 3.915(1.178∼13.007) | 4.391(0.536∼35.971) |
| tumor metastasis | ||||
| Yes | 6(4.55) | 126(95.45) | 1.000 | 1.000 |
| No | 30(3.50) | 828(96.50) | 0.761(0.310∼1.865) | 0.764(0.164∼3.606) |
a: OR (95% CI) not adjusted; b: OR (95% CI) adjusted for age, gender, nations, smoking, alcohol consumption, HBV infection, and HCC family history.