Table 7. The associations between rs4149867 and clinical characteristics of hepatocellular carcinoma patients.
| Variables | AA | AG/GG | OR(95%CI)a | OR(95%CI)b |
|---|---|---|---|---|
| tumor size | ||||
| ≥5cm | 165(67.07) | 81(32.93) | 1.000 | 1.000 |
| <5cm | 501(67.34) | 243(32.66) | 1.125(0.533∼2.373) | 0.638(0.357∼1.138) |
| tumor number | ||||
| solitary | 609(69.76) | 264(30.24) | 1.000 | 1.000 |
| multiple | 78(66.66) | 39(33.34) | 1.153(0.765∼1.739) | 1.080(0.521∼2.238) |
| TNM staging | ||||
| T1+T2 | 588(70.25) | 249(29.75) | 1.000 | 1.000 |
| T3+T4 | 96(64.00) | 54(36.00) | 1.328(0.922∼1.913) | 1.250(0.646∼2.419) |
| Combined with liver cirrhosis | ||||
| Yes | 273(65.94) | 141(34.06) | 1.000 | 1.000 |
| No | 414(72.25) | 159(27.05) | 0.744(0.566∼0.977) | 0.781(0.480∼1.270) |
| AFP level (ng/ml) | ||||
| ≥400 | 483(69.40) | 213(30.60) | 1.000 | 1.000 |
| <400 | 204(69.39) | 90(30.61) | 1.000(0.744∼1.345) | 0.988(0.587∼1.665) |
| tumor metastasis | ||||
| Yes | 99(75.00) | 33(25.00) | 1.000 | 1.000 |
| No | 582(68.31) | 270(31.69) | 0.719(0.472∼1.093) | 0.726(0.348∼1.515) |
a: OR (95% CI) not adjusted; b: OR (95% CI) adjusted for age, gender, nations, smoking, alcohol consumption, HBV infection, and HCC family history.