Table 8. The associations between rs4149963 and clinical characteristics of hepatocellular carcinoma patients.
| Variables | AA | AG/GG | OR(95%CI)a | OR(95%CI)b |
|---|---|---|---|---|
| tumor size | ||||
| ≥5cm | 218(88.62) | 28(11.38) | 1.000 | 1.000 |
| <5cm | 669(89.91) | 75(10.08) | 1.146(0.723∼1.815) | 1.648(0.775∼3.508) |
| tumor number | ||||
| solitary | 780(89.34) | 93(10.65) | 1.000 | 1.000 |
| multiple | 104(88.89) | 13(11.11) | 1.048(0.567∼1.940) | 1.610(0.614∼4.220) |
| TNM staging | ||||
| T1+T2 | 738(88.17) | 99(11.83) | 1.000 | 1.000 |
| T3+T4 | 131(87.33) | 19(2.67) | 1.081(0.640∼1.828) | 0.586(0.189∼1.814) |
| Combined with liver cirrhosis | ||||
| Yes | 360(86.96) | 51(13.04) | 1.000 | 1.000 |
| No | 516(90.05) | 57(9.95) | 0.780(0.522∼1.164) | 0.759(0.378∼1.527) |
| AFP level (ng/ml) | ||||
| ≥400 | 603(86.64) | 93(13.36) | 1.000 | 1.000 |
| <400 | 252(85.71) | 42(14.29) | 1.081(0.730∼1.601) | 0.420(0.168∼1.049) |
| tumor metastasis | ||||
| Yes | 117(88.64) | 15(11.36) | 1.000 | 1.000 |
| No | 762(88.81) | 96(11.19) | 1.018(0.571∼1.814) | 1.308(0.506∼3.382) |
a: OR (95% CI) not adjusted; b: OR (95% CI) adjusted for age, gender, nations, smoking, alcohol consumption, HBV infection, and HCC family history.