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. 2016 Nov 24;7(52):87271–87283. doi: 10.18632/oncotarget.13536

Figure 1. DHA depresses the Warburg effect, migration and invasion of NSCLC.

Figure 1

A., DHA inhibits NSCLC cell (A540 and H1975) viability in dose-dependent manner. B., DHA inhibits cell migration in the wound-healing assay. Shown here are representative images of three independent experiments. C and D., DHA inhibits A549 and H1975 cells migration and invasion in a Transwell assay. The representative photographs of migration and invasion cells were shown as C and D, respectively. E., DHA decreases glucose uptake, cell ATP content and lactate levels in A549 and H1975 cells. Columns, mean of three determinations; bars, SD. *, P < 0.05; **, P < 0.01, control versus DHA-treated cells.