Table 2. Targeted NGS analysis of NBLW and NBLW-R.
Cell line | Gene | Chromosome | Alt variant read | Codon change | Amino acid change |
---|---|---|---|---|---|
NBLW | ALK | 2 | 41.8% | cGa/cTa | R1275L |
NF1 | 17 | 98.5% | Gaa/Taa | E91-1 | |
NBLW-R | ALK | 2 | 42.4% | ttC/ttA | F1174L |
PTPRD | 9 | 61.6% | cCt/cAt | P711H |
Alt, Alternative; 1 Stop codon