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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Crit Care Med. 2017 Apr;45(4):645–652. doi: 10.1097/CCM.0000000000002268

Table 3.

Primary and secondary outcomes according to study group

Outcome Pre-intervention group (n= 186) Intervention group (n= 43) Adjusted Odds Ratio or Between-Group Difference (95% CI) P value*

Primary outcome, n (%)
  Mortality 102 (54.8) 17 (39.5) 0.36 (0.16 – 0.82) 0.02

Secondary outcomes (days)
 Ventilator-free 7.7 (9.9) 11.6 (10.8) 4.0 (7.3 to 0.6) 0.03
 ICU-free 7.2 (9.4) 9.1 (9.2) 1.9 (5.0 to −1.2) 0.23
 Hospital-free 4.0 (6.3) 5.7 (7.7) 1.6 (4.2 to −0.9) 0.20
*

P value for the primary outcome measure was a Wald test estimated using a logistic regression model accounting for age, cirrhosis, body mass index, mean arterial pressure, lactate, illness severity, sepsis, shock, oxygenation on day of ARDS onset, and intensive care unit tidal volume by time.

*

P values for the secondary outcomes are from the independent sample t-test

CI: confidence interval; ICU: intensive care unit