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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Curr Genet. 2016 Sep 14;63(3):389–400. doi: 10.1007/s00294-016-0649-4

Fig. 4.

Fig. 4

Widely separated repeats are detected by RIP in the absence of Spo11 and MEI-3. Each parental strain carries a pair hygromycin-resistance cassettes (hph) replacing spo11 and mei-3 genes. All parental hph cassettes have the original sequence introduced by the Neurospora Genome Project (Colot et al. 2006). RIP mutation of the hph cassettes replacing the mei-3 gene was assessed in the same progeny spores used previously to analyze mutation of closely positioned repeats (Gladyshev and Kleckner 2014)