Table 1.
Genes associated with increased risk of cannabis dependence and psychosis.
| Cannabis dependence genes | ||
| Gene | Function | SNPs |
| RP11-206M11.7 | Unknown | rs143244591 |
| SLC35G1 | Nucleotide sugar transport | rs146091982 |
| CSMD1 | Complement system regulation | rs77378271 |
| CNR1 | Endocannabinoid signaling | rs806380 |
| FAAH | Endocannabinoid metabolism | rs324420 |
| NRG1 | Neurotrophic factor | rs17664708 |
| MDR1 | Drug efflux pump | rs1045642 |
| Cannabis psychosis genes | ||
| Gene | Function | SNPs |
| DRD2 | Dopamine signaling | rs1076560 |
| BDNF | Neurotrophic factor | rs6265 |
| AKT1 | Kinase signaling | rs2494732 |
| COMT | Dopamine metabolism | rs4680 |