Table 3.
Swine leukocyte antigen (SLA) haplotypes and corresponding alleles identified in Canadian specific pathogen-free Yorkshire and Landrace pigs.
| SLA haplotype [International Society for Animal Genetics (ISAG) Nomenclature] | Class I loci |
Class II loci |
No. of pigs/haplotype frequency (%) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| SLA-1 | SLA-3 | SLA-2 | DRB1 | DQB1 | Ya | La | Y × La | L × Ya | |
| 2n = 256 | 2n = 358 | 2n = 62 | 2n = 58 | ||||||
| Hp-1a.15b | 01:01 | 01:01 | 01:01 | 04:02 | 02:02 | 25/9.8 | |||
| Hp-4a.4a | 04:01:01 | 04:01 | 04:01 | 02:01:01 | 04:01:01 | 67/26.2 | 17/27.4 | 9/15.5 | |
| Hp-4b.5 | 04:01:01 | 04:01 | 04:02:01 | 05:01 | 02:01 | 26/7.3 | |||
| Hp-6.12b | 08:05 | 06:01 | 05:04 | 06:01 | 07:01:01 | 26/7.3 | |||
| Hp-7.8b | 08:01 | 07:01:01 | 05:02 | 08:01 | 02:03 | 36/10.0 | 5/8.1 | ||
| Hp-7.23 | 08:01 | 07:01:01 | 05:02 | 10:01 | 06:01 | 31/8.6 | |||
| Hp-21.22 | 07:03 | 06:01 | 05:05 | 06:07 | 02:12 | 18/7.0 | 4/6.5 | ||
| Hp-26a.23 | 08:08 | 05:02 | 10:05 | 10:01 | 06:01 | 7/2.7 | 7/12.1 | ||
| Hp-26b.23 | 08:11 | 05:02 | 10:06 | 10:01 | 06:01 | 76/29.7 | 12/3.4 | 13/22.4 | |
| Hp-28.8b | 09:01b, 15:01 | 07:01:02 | 05:03 | 08:01 | 02:03 | 6/1.7 | |||
| Hp-28.23 | 09:01b, 15:01 | 07:01:02 | 05:03 | 10:01 | 06:01 | 48/13.4 | 11/17.7 | 14/24.1 | |
| Hp-32.12b | 07:02 | 04:02 | 02:02 | 06:01 | 07:01:01 | 74/20.7 | 4/6.5 | 15/25.9 | |
| Hp-35.23 | 12:01, 13:01 | 05:02 | 10:01 | 10:01 | 06:01 | 19/7.4 | 6/1.7 | 10/16.1 | |
| Hp-37.24 | 07:04 | 05:06 | 09:05 | 07:01 | 02:01 | 11/4.3 | |||
| Hp-58.2 | 08:07 | 03:06 | 09:03 | 02:01:01 | 02:01 | 6/2.3 | |||
| Hp-62.12a | 14:01 | 04:04 | 06:02:01 | 06:02 | 07:01:01 | 27/7.5 | 10/16.1 | ||
| Hp-63.27 | 08:12, 11:03 | 05:03:02 | 16:03 | 09:01:01 | 09:01 | 26/10.2 | |||
| Hp-64.23 | 14:01 | 05:02 | 10:04 | 10:01 | 06:01 | 33/9.2 | 1/1.6 | ||
| Hp-73.12b | 15:01 | 04:02 | 02:02 | 06:01 | 07:01:01 | 31/8.6 | |||
| Recombinant haplotype | |||||||||
| Hp-NA.12bc | 09:01b, 15:01 | 04:02 | 02:02 | 06:01 | 07:01:01 | 1/0.3 | |||
| Hp-64.8b | 14:01 | 05:02 | 10:04 | 08:01 | 02:03 | 1/0.3 | |||
| Hp-26b.4a | 08:11 | 05:02 | 10:06 | 02:01:01 | 04:01:01 | 1/0.4 | |||
aY, Yorkshire; L, Landrace; Y × L, Yorkshire Landrace cross; L × Y, Landrace Yorkshire cross.
bSLA-1*09:01 was detected by PCR-sequence-specific primers but missed by mRNA sequence-based typing.
cNA, official designation of the crossover class I haplotypes was not assigned by the ISAG SLA Nomenclature Committee.