Table 1.

Cardiovascular genetics next-generation sequencing (NGS) panel gene content.

NGS sub-panel	Number of genes	Genes covered
Comprehensive cardiomyopathy (CMP) and reflex CMP	61	ABCC9, ACTC1, ACTN2, ANKRD1, BAG3, CASQ2, CAV3, CRYAB, CSRP3, CTNNA3, DES, DMD, DSC2, DSG2, DSP, DTNA, EMD, EYA4, FHL1, FHL2, FKTN, GATAD1, GLA, JPH2, JUP, KLF10, LAMA4, LAMP2, LDB3, LMNA, MYBPC3, MYH6, MYH7, MYL2, MYL3, MYLK2, MYOZ2, NEBL, NEXN, PDLIM3, PKP2, PLN, PRKAG2, PSEN1, PSEN2, RAF1, RBM20, RYR2, SCN5A, SGCD, TAZ, TCAP, TMEM43, TMPO, TNNC1, TNNI3, TNNT2, TPM1, TTN, TTR, VCL
Hypertrophic cardiomyopathy	18	ACTC1, ACTN2, CSRP3, GLA, LAMP2, MYBPC3, MYH7, MYL2, MYL3, MYOZ2, NEXN, PLN, PRKAG2, TNNC1, TNNI3, TNNT2, TPM1, TTR
Dilated cardiomyopathy	33	ABCC9, ACTC1, ACTN2, ANKRD1, BAG3, CRYAB, CSRP3, DES, DMD, DTNA, EMD, EYA4, GATAD1, LAMP2, LDB3, LMNA, MYBPC3, MYH7, NEXN, PLN, RAF1, RBM20, SCN5A, SGCD, TAZ, TCAP, TNNC1, TNNI3, TNNT2, TPM1, TTN, TTR, VCL
Arrythmogenic right ventricular cardiomyopathy	8	CTNNA3, DSC2, DSG2, DSP, JUP, LMNA, PKP2, TMEM43
Marfan syndrome and Loeys–Dietz syndrome	3	FBN1, TGFBR1, TGFBR2
Thoracic aortic aneurysms and dissections (TAAD) and reflex TAAD	18	ACTA2, CBS, COL3A1, COL5A1, COL5A2, ELN, FBN1, FBN2, MED12, MYH11, MYLK, PLOD1, SLC2A10, SMAD3, SMAD4, TGFB2, TGFBR1, TGFBR2