. 2017 Mar 15;4:11. doi: 10.3389/fcvm.2017.00011

Table 3.

Corrected SNP performance validation in 1-plex comprehensive comprehensive cardiomyopathy (CMP) panel validation after BigDye sequencing.

Metrics	TruSight One panel	CMP and reflex	Hypertrophic cardiomyopathy	Dilated cardiomyopathy/left ventricular non-compaction	Arrhythmogenic right ventricular cardiomyopathy	Marfan syndrome/Loeys–Dietz syndrome	Thoracic aortic aneurysms and dissections and reflex
Analytical sensitivity	N/A^a	1.00 ± 0.00	1.00 ± 0.00	1.00 ± 0.00	1.00 ± 0.00	N/A^a	1.00 ± 0.00
Analytical specificity	N/A^a	0.99 ± 0.00	1.00 ± 0.00	0.99 ± 0.00	1.00 ± 0.00	N/A^a	1.00 ± 0.00
False negative (FN) SNP rate	N/A^a	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	N/A^a	0.00 ± 0.00
False positive (FP) SNP rate	N/A^a	0.01 ± 0.00	0.00 ± 0.00	0.01 ± 0.00	0.00 ± 0.00	N/A^a	0.00 ± 0.00

^aMeasurements not calculated for the designated panels (no BigDye sequencing performed).