Table 1.

Cell subtypes in lung after live vaccine strain infection.

	C57Bl/6	SCL11A1+	TLR2/4/9−/− SLC11A1+	C57Bl/6	SLC11A1+	TLR2/4/9−/− SLC11A1+	C57Bl/6	SLC11A1+	TLR2/4/9−/− SLC11A1+
	Day 0	Day 0	Day 0	Day 3	Day 3	Day 3	Day 5	Day 5	Day 5
Total cells/lobe	3.40 × 106 ± 2.08 × 105	3.50 × 106 ± 1.73 × 105	3.50 × 106 ± 1.73 × 105	6.77 × 106 ± 2.60 × 105	3.53 × 106 ± 6.67 × 104	5.33 × 106 ± 6.67 × 104	7.63 × 106 ± 2.61 × 105	3.67 × 106 ± 2.60 × 105	4.40 × 106 ± 2.60 × 105
		NS	NS		p = 0.0006	p = 0.0120		p = 0.0002	p = 0.0006
Neutrophils (CD3−, CD19−, CD11cVar, CD11b+, Gr-1+)	9.79 × 104 ± 1.06 × 104	8.64 × 104 ± 1.11 × 104	7.77 × 104 ± 2.33 × 104	1.23 × 106 ± 3.49 × 105	2.45 × 105 ± 2.03 × 104	4.13 × 105 ± 9.88 × 104	7.63 × 106 ± 2.60 × 105	2.30 × 105 ± 5.57 × 104	4.24 × 105 ± 2.00 × 104
		NS	NS		NS	NS		p < 0.0001	p < 0.0001
Macrophages (CD3−, CD19−, CD11cVar, CD11b+, Gr-1− F4/80low)	8.91 × 104 ± 6.28 × 103	8.57 × 104 ± 2.99 × 103	9.32 × 104 ± 8.42 × 103	4.48 × 105 ± 7.26 × 104	1.78 × 105 ± 1.93 × 104	2.35 × 105 ± 8.24 × 103	6.37 × 105 ± 2.14 × 105	1.79 × 105 ± 4.79 × 104	1.51 × 105 ± 1.50 × 104
		NS	NS		p = 0.046	NS		NS	NS
Macrophages (CD3−, CD19−, CD11cVar, CD11b+, Gr-1− F4/80mid)	8.75 × 105 ± 4.74 × 103	8.07 × 105 ± 1.57 × 104	5.15 × 105 ± 8.39 × 103	1.41 × 105 ± 8.44 × 104	6.90 × 104 ± 4.09 × 103	1.48 × 105 ± 3.06 × 103	7.07 × 104 ± 1.66 × 104	6.11 × 104 ± 1.53 × 104	9.35 × 104 ± 3.21 × 104
		NS	NS		NS	NS		NS	NS
Dendritic cells (CD3−, CD19−, CD11c+, CD11b−, F4/80low)	1.21 × 104 ± 2.44 × 102	1.41 × 104 ± 1.13 × 103	1.60 × 104 ± 4.39 × 103	4.59 × 104 ± 1.42 × 104	1.71 × 104 ± 8.83 × 102	2.62 × 104 ± 7.49 × 102	5.11 × 104 ± 2.05 × 104	2.03 × 104 ± 1.85 × 103	2.45 × 104 ± 4.09 × 103
		NS	NS		NS	NS		NS	NS
Alveolar macrophages (CD3−, CD19−, CD11c+, CD11b−, F4/80mid)	5.22 × 104 ± 3.66 × 103	5.25 × 104 ± 1.00 × 104	4.37 × 104 ± 9.84 × 103	1.15 × 105 ± 2.68 × 104	9.70 × 104 ± 1.45 × 103	2.36 × 105 ± 6.461 × 103	3.22 × 104 ± 6.01 × 103	4.76 × 104 ± 3.79 × 103	9.97 × 104 ± 1.90 × 104
		NS	NS		NS	p = 0.0234		NS	NS

Summary of total number of each cell type in the lungs of infected mice. Significant differences were made by comparing each strain to B6 at that time point (NS = not significant). A Student’s t-test corrected for multiple comparisons was used to calculate significance. N = 3 mice per time point.