FIGURE 1.

Effects of DEX administration on liver injury parameters induced by INH/LPS co-administration. Rats were treated with INH 200 or 400 mg/kg for 14 consecutive days, at day 14 they were given 4 mg/kg DEX 1 h earlier before they received 2 mg/kg LPS dose followed by INH 2 h later. (A) Effects on body weight. (B) Liver weight variation. (C) Impact on serum TBA and TBil levels. (D) Alterations in serum ALT, AST, and GGT levels. Data were represented as mean ± SD, n = 8 for each bar. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001 versus control, ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 versus INH/LPS combination.