Table 2.
DAPI positive nuclei (C18) | |||
---|---|---|---|
Time of exposure (h) | 0 | 1 | 12 |
TC2153 | 100 ± 7.7 | 102 ± 13.5 | 64 ± 4.8* |
BVT948 | 100 ± 6.9 | 61 ± 7.3* | 33 ± 6.8** |
Sunitinib | 100 ± 3.3 | 101 ± 7.2 | 97 ± 8.1 |
PP2 | 100 ± 11 | 74 ± 9.1 | 85 ± 9.9 |
The toxicity of the Tyr kinase and Tyr phosphatase inhibitors was assessed by counting the number of DAPI positive nuclei (10 fields per slides. N = 5; Two tailed T-test).
P < 0.05 vs. time 0 and
P < 0.005 vs. time 0.