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. 2017 Mar 15;10:59. doi: 10.3389/fnmol.2017.00059

Table 2.

Neuronal survival after exposure to Tyr phosphatase and Tyr kinase inhibitors.

DAPI positive nuclei (C18)
Time of exposure (h) 0 1 12
TC2153 100 ± 7.7 102 ± 13.5 64 ± 4.8*
BVT948 100 ± 6.9 61 ± 7.3* 33 ± 6.8**
Sunitinib 100 ± 3.3 101 ± 7.2 97 ± 8.1
PP2 100 ± 11 74 ± 9.1 85 ± 9.9

The toxicity of the Tyr kinase and Tyr phosphatase inhibitors was assessed by counting the number of DAPI positive nuclei (10 fields per slides. N = 5; Two tailed T-test).

*

P < 0.05 vs. time 0 and

**

P < 0.005 vs. time 0.