Table 3.
≥1 PIMs/PPOs according to | ≥1 clinically relevant PIMs/PPOs according to | |||||
---|---|---|---|---|---|---|
STOPP/START | STOPP | START | STOPP/START | STOPP | START | |
Age | 1.05 (0.98; 1.12) | 1.02 (0.97; 1.08) | 1.02 (0.97; 10.7) | 0.99 (0.93; 1.04) 1.04 (0.98; 1.10) | 1.01 (0.96; 1.06) 1.04 (0.98; 1.10) | 0.98 (0.93; 1.03) 1.03 (0.98; 1.08) |
Sex | 0.73 (0.28; 1.92) | 0.59 (0.27; 1.29) | 0.81 (0.42; 1.58) | 0.80 (0.37; 1.70) 0.72 (0.30; 1.73) | 1.24 (0.62; 2.46) 0.66 (0.31; 1.42) | 1.05 (0.55; 2.01) 0.97 (0.52; 1.80) |
MDD | 10.6 (1.60; 70.1) | 2.55 (0.87; 7.48) | 2.23 (0.89; 5.60) | 7.95 (2.35; 26.9) 6.96 (1.50; 32.3) | 2.90 (1.14; 7.38) 2.50 (0.88; 7.09) | 1.82 (0.77; 4.30) 2.01 (0.86; 4.72) |
Impaired cognition | 1.28 (0.37; 4.40) | 0.95 (0.37; 2.42) | 1.52 (0.68; 3.39) | 0.54 (0.20; 1.45) 1.13 (0.38; 3.38) | 0.69 (0.30; 1.59) 0.94 (0.38; 2.34) | 1.03 (0.48; 2.24) 1.23 (0.59; 2.58) |
Nursing home resident | 0.29 (0.05; 1.77) | 1.31 (0.44; 3.99) | 0.46 (0.19; 1.16) | 0.52 (0.17; 1.63) 0.22 (0.05; 1.00) | 1.17 (0.47; 2.89) 0.95 (0.33; 2.72) | 0.60 (0.27; 1.35) 0.34 (0.15; 0.76) |
Number of drugs | 1.28 (1.11; 1.48) | 1.35 (1.19; 1.53) | 1.08 (0.99; 1.17) | 1.28 (1.14; 1.43) 1.24 (1.09; 1.40) | 1.27 (1.15; 1.41) 1.37 (1.21; 1.54) | 1.08 (0.99; 1.17) 1.03 (0.96; 1.12) |
Figures in italics represent results in the sensitivity analysis where not assessable PIMs/PPOs were categorized as clinically relevant. Odds ratios which do not cross the line of unity are underlined
STOPP screening tool of older person’s potentially inappropriate prescription, START screening tool to alert to right treatment, MDD multi-dose drug dispensing